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The Avene Tolerance Control Cream is highly recommended for those with sensitive skin who are using Tretinoin. Kenzie, the reviewer, has been using this cream as a spot moisturizer on specific areas of her face while transitioning to Tretinoin. The cream's composition mimics the skin's natural composition and contains squalane, which is also found in our skin. It is formulated to avoid aggravating Malassezia filagelitis. Kenzie has not experienced any negative reactions or bumps since using this cream. Overall, the Avene Tolerance Control Cream is a thick and soothing moisturizer that effectively caters to sensitive skin's needs.